Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Desquamative Interstitial Pneumonia (DIP)
- Radiologic Findings
- Fig 1. Chest PA shows suspicious diffuse patchy ground-glass opacity in both lungs.
Fig 2-4. CT scans reveals diffuse symmetric ground-glass opacity in both lungs.
Fig 5. [1 year later] CT scan shows no change of diffuse ground-glass opacity and newly appeared multiple small air cysts in both lungs.
Fig 6. [4 years later] CT scan shows ground-glass opacity with aggravating multiple small air cysts, reticulation, and linear opacities in both lungs.
- Brief Review
- Desquamative interstitial pneumonia (DIP) is characterized by the accumulation of numerous pigmented macrophages within most of the distal airspace of the lung and, sometimes, the presence of giant cells. DIP is usually associated with tobacco smoke. However, the association between smoking and DIP is less robust than that with respiratory bronchiolitis with interstitial lung disease or pulmonary Langerhans cell histiocytosis; approximately 10
- Please refer to
Case 4, Case 266, Case 615, Case 620, Case 840, Case 1127, Case 1149, -
KSTR Imaging Conference 2004 Spring Case 8
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KSTR Imaging conference 2010 Summer Case 19
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KSTR Imaging Conference 2011 Spring Case 6,
- References
- 1. Godbert B, Wissler MP, Vignaud JM. Desquamative interstitial pneumonia: an analytic review with an emphasis on aetiology, Eur Respir Rev. 2013 Jun 1;22(128):117-23.
2. Attili AK, Kazerooni EA, Gross BH, et al. Smoking-related Interstitial Lung Disease: Radiologic-Clinical-Pathologic Correlation. Radiographics. 2008 Sep-Oct;28(5):1383-96.
3. Iwasawa T, Takemura T, Ogura T. Smoking-related lung abnormalities on computed tomography images: comparison with pathological findings. Jpn J Radiol. 2018 Mar;36(3):165-180.
- Please refer to
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- Keywords
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lung, interstitial pneumonia, smoking related ILD, desquamative interstitial pneumonia,